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Tests of sweating and cardiovascular reflexes in patients with distal small fiber neuropathy

  • J. D. Stewart
  • P. A. Low
  • R. D. Fealey
Conference paper

Summary

Distal small fiber neuropathy (DSFN) was diagnosed in 40 patients using the criteria of dysesthesias in the extremities, distal sensory abnormalities of pinprick and temperature greater than touch, vibration and joint position. Patients with more than minor distal muscle weakness and ankle hyporeflexia, or with abnormal nerve conduction and electromyographic studies were excluded. Quantitative sudomotor axon reflex testing (QSART) was abnormal in 32/40 (80%) patients. Thermoregulatory sweat testing (TST) showed a peripheral neuropathic pattern in 18/25 (72%) patients. One or other test was abnormal in 36/40 (90%) patients. Cardiovascular autonomic reflexes (heart rate changes on deep breathing and Valsalva maneuver) were abnormal in 11/40 (28%) patients.

Keywords

Peripheral Neuropathy Sweat Gland Monoclonal Gammopathy Cardiovascular Autonomic Neuropathy Sympathetic Skin Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Wien 1995

Authors and Affiliations

  • J. D. Stewart
    • 1
  • P. A. Low
    • 2
  • R. D. Fealey
    • 2
  1. 1.Montreal Neurological InstituteMontrealCanada
  2. 2.Department of NeurologyMayo ClinicRochesterUSA

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