Peripheral nerve dysfunction in chronic obstructive pulmonary disease
48 patients with chronic obstructive pulmonary disease (COPD) have been investigated in regard to clinical and electrophysiological signs of peripheral nerve dysfunction. None of the COPD patients had any obvious cause of peripheral neuropathy. Diagnosis of definite peripheral neuropathy clinical and subclinical — has been done in 27% of the hypoxemic COPD patients vs 9% of the normoxemic COPD patients.
The mean values of the median and peroneal nerve conduction velocities were significantly lower in the hypoxemic COPD group with neuropathy than in those without.
Diagnosis of PN was significantly correlated with PaO2 respectively the degree of hypoxemia in the hypoxemic COPD patients. PaO2 was a significant predictor variable for discrimination between patients with and without peripheral neuropathy.
KeywordsChronic Obstructive Pulmonary Disease Peripheral Neuropathy Chronic Obstructive Pulmonary Disease Patient Conduction Velocity Chronic Hypoxia
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