Rotavirus structure: interactions between the structural proteins

  • A. L. Shaw
  • R. Rothnagel
  • C. Q.-Y. Zeng
  • J. A. Lawton
  • R. F. Ramig
  • M. K. Estes
  • B. V. Venkataram Prasad
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 12)


Structural studies on rotavirus using electron cryomicroscopy and computer image analysis have permitted visualization of each shell in the triple-layered rotavirus structure. Biochemical results have aided our interpretation of the structural organization of these layers and protein interactions seen in the three-dimensional structure, and have provided a better understanding of the structure-function relationships of the rotavirus structural proteins.


Computer Image Analysis Computer Image Processing Aqueous Channel Electron Cryomicroscopy Icosahedral Lattice 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 1996

Authors and Affiliations

  • A. L. Shaw
    • 1
  • R. Rothnagel
    • 1
  • C. Q.-Y. Zeng
    • 2
  • J. A. Lawton
    • 3
  • R. F. Ramig
    • 2
  • M. K. Estes
    • 2
  • B. V. Venkataram Prasad
    • 1
  1. 1.Verna and Marss McLean Department of Biochemistry and the W.M. Keck Center for Computational BiologyHoustonUSA
  2. 2.Division of Molecular VirologyHoustonUSA
  3. 3.Program in Cell and Molecular BiologyHoustonUSA

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