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Viral factors determining rotavirus pathogenicity

  • U. Desselberger
Conference paper

Summary

The pathogenicity of rotaviruses depends on multiple viral and host factors. Evidence is presented for the involvement of a number of viral genes (coding for structural and non-structural proteins) in the ability of the virus to cause diarrhoea. Different genes are important in different rotavirus-host systems suggesting that there is no single viral pathogenicity factor.

Keywords

Outer Capsid Protein Host Range Restriction Gnotobiotic Piglet 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Wien 1997

Authors and Affiliations

  • U. Desselberger
    • 1
  1. 1.Clinical Microbiology and Public Health LaboratoryAddenbrooke’s HospitalCambridgeUK

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