Naturally Occurring 6-Substituted 5,6-Dihydro-α-Pyrones

  • L. A. Collett
  • M. T. Davies-Coleman
  • D. E. A. Rivett
Part of the Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products book series (FORTCHEMIE (closed), volume 75)


6-Substituted derivatives of 5,6-dihydro-α-pyrones (dihydropyran-2ones or more specifically 2H-dihydropyran-2-ones) occur widely in nature, particularly in plants and bacteria. They possess an α, β unsaturated-δ-ring (1) with an alkyl, alkenyl or aryl substituent at C-6 and occasionally a varied substitution pattern around the ring. Many of these compounds are biologically active, exhibiting phytotoxicity, cytotoxicity against tumour cells and antifungal or antimicrobial activity.


Circular Dichroism Spectrum Absolute Configuration Total Synthesis Stereoselective Synthesis Tetrahedron Letter 
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Copyright information

© Springer-Verlag Wien 1998

Authors and Affiliations

  • L. A. Collett
    • 1
  • M. T. Davies-Coleman
    • 1
  • D. E. A. Rivett
    • 1
  1. 1.Department of ChemistryRhodes UniversityGrahamstownSouth Africa

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