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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products pp 1–179Cite as

Cyclopeptide Alkaloids

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Abstract

Cyclopeptide alkaloids are defined as basic compounds embodying an ansa structure, in which a 10- or 12-membered peptide type bridge spans the 1,3 or 1,4 positions of a benzene ring (1). They are widely distributed among plants of the Rhamnaceae family, but their occurrence has also been confirmed in representatives of Asteraceae, Celastraceae, Euphorbiaceae, Menispermaceae, Pandaceae, Rubiaceae, Sterculiaceae and Urticaceae. These compounds are found in leaves, stem bark, root bark and seeds. They often occur in minute amounts and as complex mixtures. The total yield from dried plant material is between 0.01 and 1% and depends on many factors such as the region of growth, the season of collection, the maturity of the plant used as well as the method of isolation (2–6).

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Authors and Affiliations

  1. Laboratory of Pharmacognosy, Department of Pharmacy, Aristotelian University of Thessaloniki, Thessaloniki, Greece

    D. C. Gournelis

  2. Division of Pharmacognosy, Leiden/Amsterdam Center for Drug Research, Leiden, The Netherlands

    G. G. Laskaris & R. Verpoorte

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  1. Department of Chemistry, The Florida State University, Tallahassee, Florida, USA

    W. Herz

  2. Institut für Chemie, Johannes-Kepler-Universität, Linz, Austria

    H. Falk

  3. Chemistry Department, The University of Glasgow, Glasgow, Scotland

    G. W. Kirby

  4. Department of Chemistry, University of Hawaii at Manoa, Honolulu, Hawaii, USA

    R. E. Moore

  5. Institut für Organische Chemie der Universität Basel, Basel, Switzerland

    Ch. Tamm

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Gournelis, D.C., Laskaris, G.G., Verpoorte, R. (1998). Cyclopeptide Alkaloids. In: Herz, W., Falk, H., Kirby, G.W., Moore, R.E., Tamm, C. (eds) Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, vol 75. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6507-2_1

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