Novel approaches to the treatment of post compressive spinal cord injury

  • W. F. Young
  • D. Dominique
  • U. S. Vasthare
  • R. F. Tuma


Spinal cord injuries are an important cause of longterm disability with current estimates of their frequency at a range of 30-50 cases per million population. Over the last decade, our knowledge of the pathophysiological mechanisms associated with spinal cord injury has increased dramatically. Clinical and basic science research have improved our ability to preserve and restore function following these devastating injuries. In this chapter, we will briefly review some of the important advancements that have been gained through basic science research, and in particular review our experimental findings utilizing a model of compressive spinal cord injury.


Spinal Cord Spinal Cord Injury Hemorrhagic Shock Hypertonic Saline Acute Spinal Cord Injury 
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Copyright information

© Springer-Verlag Wien 1998

Authors and Affiliations

  • W. F. Young
    • 1
  • D. Dominique
    • 1
  • U. S. Vasthare
    • 1
  • R. F. Tuma
    • 1
  1. 1.Department of NeurosurgeryTemple University HospitalPhiladelphiaUSA

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