Zusammenfassung
Steele, Richardson und Olszewksi beschrieben 1964 die nach ihnen benannte progressive supranukleäre Blickparese (progressive-supranuclear palsy — PSP) als eine klinisch-pathologisch abgrenzbare neurodegenerative Erkrankung (Steele et al. 1964). Vereinzelte klinische oder pathologische Berichte gehen jedoch z. T. um Jahrzehnte voraus (Goetz 1996). Die PSP ist neuropathologisch durch das Auftreten zahlreicher neurofibrillärer Bündel bzw. sog. „neuropil threads“ in bestimmten Regionen der Basalganglien und des Hirnstamms gekennzeichnet. Neuronaler Zellverlust und Gliose sind variabel ausgeprägt.
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Wenning, G.K., Poewe, W. (1999). Exkurs: Progressive supranukleäre Blickparese. In: Riederer, P., Laux, G., Pöldinger, W. (eds) Neuro-Psychopharmaka Ein Therapie-Handbuch. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6400-6_41
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