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Part of the book series: Journal of Neural Transmission. Supplementa ((NEURAL SUPPL,volume 56))

Summary

Although most neurologists accept that Parkinson’s disease (PD) is a unique disorder, we still lack a valid diagnostic biological tool and therefore depend primarily on clinical examination in diagnosis. The distinction between PD and other parkinsonian syndromes is discussed.

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References

  • Calne DB (1989) Is “Parkinson’s disease” one disease? J Neurol Neurosurg Psychiatry [Suppl]: 18–21

    Google Scholar 

  • Gasser T, Müller-Myhsok B, Wszolek ZK, Ochlmann R, Calne DB, Bonifati V, Bereznai B, Fabrizio E, Vieregge P, Horstmann RD (1998) A susceptibility locus for Parkinson’s disease maps to chromosome 2p13. Letter — Nat Genet 18: 262–265

    Article  CAS  Google Scholar 

  • Hughes AJ, Daniel SE, Blankson S, Lees AJ (1993) A clinicopathologic study of 100 cases of Parkinson’s disease. Arch Neurol 50: 140–148

    Article  PubMed  CAS  Google Scholar 

  • Inzelberg R, Korczyn AD (1994) Parkinsonism in adult-onset GM2 gangliosidosis. Mov Disord 9: 375–380

    Article  PubMed  CAS  Google Scholar 

  • Inzelberg R, Flash T, Korczyn AD (1995) Kinematic analysis of complex movements in Parkinson’s disease. In: Przuntek H, Kraus PH, Klotz P, Korczyn AD (eds) Instrumental methods and scoring in extrapyramidal disorders. Springer, Berlin Heidelberg New York Tokyo, pp 181–187

    Chapter  Google Scholar 

  • Leenders KL, Salmon EP, Tyrrell P, Perani D, Brooks DJ, Sager H, Jones T, Marsden CD, Frackowiak RSJ (1990) The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson’s disease. Arch Neurol 47: 1290–1298

    Article  PubMed  CAS  Google Scholar 

  • Martin WRW, Palmer MR, Patlak CS, Calne DB (1989) Nigrostriatal function in humans studied with positron emission tomography. Ann Neurol 26: 535–542

    Article  PubMed  CAS  Google Scholar 

  • Nisipeanu P, Kuritzki A, Korczyn AD (1994) Familial levodopa responsive parkinsonian-pyramidal syndrome. Mov Disord 9: 673–675

    Article  PubMed  CAS  Google Scholar 

  • Nisipeanu P, Paleacu D, Korczyn AD (1997) Infectious and postinfectious parkinsonism. In: Watts RI, Koller WC (eds) Movement disorders: neurologic principles and practice. McGraw-Hill, New York, pp 307–312

    Google Scholar 

  • Orlov E, Grozman GB, Drory VE, Simon E, Shabtai H, Korczyn AD, Giladi N (1998) Electromyography of the anal sphincter in parkinsonism. Neurology 50 [Suppl 4]: A132

    Google Scholar 

  • Parkinson J (1817) An essay in the shaking palsy. Whittingham and Rowland, London

    Google Scholar 

  • Polymeropoulos MH, Lavedant C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum L (1997) Mutation in the α-synuclein gene identified in families with Parkinson’s disease. Science 276: 2045–2047

    Article  PubMed  CAS  Google Scholar 

  • Rajput AH, Rozdilsky B, Rajput A (1991) Accuracy of clinical diagnosis in parkinsonism — a prospective study. Can J Neurol Sci 18: 275–278

    PubMed  CAS  Google Scholar 

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© 1999 Springer-Verlag Wien

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Korczyn, A.D. (1999). Parkinson’s disease: one disease entity or many?. In: Przuntek, H., Müller, T. (eds) Diagnosis and Treatment of Parkinson’s Disease — State of the Art. Journal of Neural Transmission. Supplementa, vol 56. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6360-3_5

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  • DOI: https://doi.org/10.1007/978-3-7091-6360-3_5

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83275-2

  • Online ISBN: 978-3-7091-6360-3

  • eBook Packages: Springer Book Archive

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