Hemispheric Disconnection: Callosotomy and Hemispherotomy

  • Jean-Guy Villemure
  • Olivier Vernet
  • Olivier Delalande
Part of the Advances and Technical Standards in Neurosurgery book series (NEUROSURGERY, volume 26)


Callosotomy and hemispherotomy are both neurosurgical procedures available to disconnect the cerebral hemisphere. Callosotomy disconnects the hemispheres partly or completely, one from the other, while hemispherotomy disconnects one hemisphere from the rest of the central nervous system. Callosotomy has been in the neurosurgical armamentarium for 60 years, but gained clear recognition as a valuable surgical procedure in the treatment of epilepsy during the seventies. While anatomical hemispherectomy in humans was first carried out more than seventy five years ago, the concept of disconnection rather than removal of the cerebral hemisphere for control of seizures, became reality twenty five years ago with the introduction of functional hemispherectomy. With the hemispherotomy technique, the emphasis is placed on greater disconnection and smaller excision.


Corpus Callosum Seizure Frequency Seizure Outcome Corpus Callosotomy Functional Hemispherectomy 
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Copyright information

© Springer-Verlag/Wien 2000

Authors and Affiliations

  • Jean-Guy Villemure
    • 1
  • Olivier Vernet
    • 1
  • Olivier Delalande
    • 2
  1. 1.Neurosurgery ServiceCentre Hospitalier Universitaire VaudoisLausanneSwitzerland
  2. 2.Neurosurgery ServiceFondation Ophtalmologique Adolphe de RothschildParisFrance

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