P System

  • Helmut Schenkel-Brunner


The first antigen of the blood group P system, P 1, was discovered in 1927 by Landsteiner and Levine [66]; the system was expanded in 1935 when the antigens P [103] and P k [58,59,85] were discovered and identified as belonging to the P system. Five blood group P phenotypes can be defined according to the presence or absence of these three serological specificities on the erythrocytes, two of which, P 1, and P 2, are frequent and three, P 1 k ,P 2 k and p, very rare (Tables 8.1 and 8.2) [101]:
  • P 1, erythrocytes are characterised by the presence of P 1, and P antigen,

  • P 2 cells lack the P antigen,

  • in P and P erythrocytes the P determinant is absent and the cells show strong P k activity; the presence of P 1, antigen distinguishes the P 1 k phenotype from P 2 k ,

  • none of the three antigenic characters are detectable on p cells.


Blood Group Erythrocyte Membrane Human Erythrocyte Hydatid Cyst Neisseria Gonorrhoeae 
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© Springer-Verlag Wien 2000

Authors and Affiliations

  • Helmut Schenkel-Brunner
    • 1
  1. 1.Institut für Medizinische BiochemieUniversität WienViennaAustria

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