Carcinoembryonic Antigen (CEA) Family

  • Helmut Schenkel-Brunner


The carcinoembryonic antigen (CEA) was first described as a tumor-associated antigen found in extracts from human colon cancer tissue [9]. Originally CEA was assumed to be an oncofetal antigen, expressed during fetal development, but deficient in healthy individuals, and re-expressed only in cancer tissues. Later investigations have shown, however, that CEA is also expressed in normal adult tissue. It remains an important tumour marker, particularly because sera of patients with colorectal carcinomas or tumours of epithelial origin show increased levels of CEA [10,31].


Carcinoembryonic Antigen Neisseria Gonorrhoeae Normal Adult Tissue Oncofetal Antigen Human Digestive System 
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© Springer-Verlag Wien 2000

Authors and Affiliations

  • Helmut Schenkel-Brunner
    • 1
  1. 1.Institut für Medizinische BiochemieUniversität WienViennaAustria

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