Abstract
Brain Natriuretic Peptide (BNP) belongs to the family of natriuretic peptides, the other members being Atrial Natriuretic Peptide (ANP) and C-type Natriuretic Peptide (CNP); each type also existing in iso-forms. The average peptide length is 30 amino acid residues ranging from 20 to 54 [14]. Their systemic effects are hypotension, natriuresis and hyponatraemia, acting via specific natriuretic peptide receptors characterized on the basis of pharmacology and molecular biology [5].
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Adner M, Cantera L, Ehlert F, Nilsson L, Edvinsson L (1996) Plasticity of contractile endothelin-B receptors in human arteries after organ culture. Br J Pharmacol 119: 1159–1166
Alafaci C, Jansen I, Arbab MA, Shiokawa Y, Svendgaard NA, Edvinsson L (1990) Enhanced vasoconstrictor effect of endo-thelin in cerebral arteries from rats with subarachnoid haemorrhage. Acta Physiol Scand 138: 317–319
Berendes E, Walter M, Cullen P, Prien T, Van Aken H, Horsthemke J, Schulte M, von Wild K, Scherer R (1997) Secretion of brain natriuretic peptide in patients with aneurysmal subarachnoid haemorrhage. Lancet 349: 245–249
Espiner EA (1994) Physiology of natriuretic peptides. J Intern Med 235: 527–541
Farrell AP, Olson KR (2000) Cardiac natriuretic peptides: a physiological lineage of cardioprotective hormones? Physiol Biochem Zool 73: 1–11
Fyhrquist F, Tikkanen I (1988) Atrial natriuretic peptide in congestive heart failure. Am J Cardiol 62: 20A–24A
Garbers DL (1999) The guanylyl cyclase receptors. Methods 19: 477–484
Hansen-Schwartz J, Edvinsson L (2000) Increased sensitivity to ET-1 in rat cerebral arteries following organ culture. Neuro-report 11: 649–652
Isotani E, Suzuki R, Tomita K, Hokari M, Monma S, Marumo F, Hirakawa K (1994) Alterations in plasma concentrations of natriuretic peptides and antidiuretic hormone after subarachnoid hemorrhage. Stroke 25: 2198–2203
Kroll M, Juhler M, Lindholm J (1992) Hyponatraemia in acute brain disease. J Intern Med 232: 291–297
Leseth KH, Adner M, Berg HK, White LR, Aasly J, Edvinsson L (1999) Cytokines increase endothelin ETB receptor contractile activity in rat cerebral artery. Neuroreport 10: 2355–2359
Suga S, Nakao K, Hosoda K, Mukoyama M, Ogawa Y, Shirakami G, Arai H, Saito Y, Kambayashi Y, Inouye K (1992) Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology 130: 229–239
Sviri GE, Feinsod M, Soustiel JF (2000) Brain natriuretic peptide and cerebral vasospasm in subarachnoid hemorrhage: clinical and TCD correlations. Stroke 31: 118–122
Wijdicks EF, Schievink WI, Burnett JC, Jr. (1997) Natriuretic peptide system and endothelin in aneurysmal subarachnoid hemorrhage. J Neurosurg 87: 275–280
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© 2001 Springer-Verlag
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Hansen-Schwartz, J., Sviri, G., Edvinsson, L. (2001). Influence of Brain Natriuretic Peptide on Phenotypic Change of Cerebral Vasculature. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_9
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_9
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