Neuroprotective Treatment Paradigms in Neurovascular Surgery — Efficacy in a Rat Model of Focal Cerebral Ischemia

  • S. Zausinger
  • T. Westermaier
  • A. Baethmann
  • H.-J. Steiger
  • R. Schmid-Elsaesser
Conference paper
Part of the Acta Neurochirurgica Supplements book series (NEUROCHIRURGICA, volume 77)


Temporary occlusion of cerebral arteries facilitates many neurovascular operations, f.e. clipping of aneurysms or extirpation of arteriovenous malformations. The chance of a safe and longer interruption of cerebral perfusion would considerably widen the surgical options. The standard neuroprotective options in neurosurgery involve nimodipine, mannitol, dexamethasone, and mostly barbiturates.


Middle Cerebral Artery Occlusion Focal Cerebral Ischemia Mild Hypothermia Cereb Blood Flow Burst Suppression 
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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • S. Zausinger
    • 1
  • T. Westermaier
    • 1
  • A. Baethmann
    • 2
  • H.-J. Steiger
    • 1
  • R. Schmid-Elsaesser
    • 1
  1. 1.Department of Neurosurgery, Klinikum GrosshadernLudwig-Maximilians-UniversityMunichGermany
  2. 2.Institute for Surgical Research, Klinikum GrosshadernLudwig-Maximilians-UniversityMunichGermany

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