Abstract
Cerebral vasospasm is a prolonged vasoconstriction that develops on average 3 days after subarachnoid hemorrhage (SAH), peaks 7 to 8 days after the hemorrhage and then slowly resolves over the next 5 to 7 days [6]. Vasospasm may be initiated by erythrocyte lysis with release of hemoglobin and/or breakdown products of hemoglobin. The subsequent events that cause and then lead to the onset and reversal of the vasospasm are less certain. Vasospastic arteries have an increased tendency to spontaneously contract when placed under isometric tension although they are less responsive to contractile agents [5]. This suggests that changes in the vascular wall are critical for vasospasm.
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© 2001 Springer-Verlag
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Zhang, ZD., Marton, L.S., Ono, S., Komuro, T., Weir, B., Macdonald, R.L. (2001). Complimentary Deoxyribonucleic Acid Array Analysis of Cerebral Arteries after Experimental Subarachnoid Hemorrhage. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_4
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_4
Publisher Name: Springer, Vienna
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