Abstract
Subarachnoid hemorrhage (SAH) is one of the most devastating of all cerebrovascular disorders [10]. One of the most serious complications of SAH remains vasospasm [3, 9]. Bedside cerebral microdialysis is a recently available method to sample and directly analyze extracellular concentration of cerebral metabo- lites next to the patient [7]. It monitors the energy metabolites glucose, pyruvate and lactate, the excitatory amino acid glutamate and glycerol, a marker of cell membrane damage. The usefulness of the microdialysis technique in a clinical setting of a neurointensive care unit has been reported previously [4, 5, 6]. Since changes of brain extracellular metabolites were shown to correlate with the neurological condition, the microdialysis techniques may be powerful in monitoring the progression of ischemia in SAH patients [6].
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Sarrafzadeh, A.S., Sakowitz, O.W., Lanksch, W.R., Unterberg, A.W. (2001). Time Course of Various Interstitial Metabolites Following Subarachnoid Hemorrhage Studied by on-Line Microdialysis. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_31
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_31
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