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Experimental Basis of Cryosurgery

  • Nikolai N. Korpan
  • Jaroslav V. Zharkov

Abstract

Advances in cryosurgical technology have further stimulated interest in the use of cryosurgery to treat different diseases, first and foremost malignancies. The effect of different temperature applications on the freeze-thawing process in vitro to evaluate modern cryosurgical techniques as a treatment option for diseases of different organs, primarily for malignant tumors, has not yet been investigated. The effect of freeze-thawing processes using temperatures of varying intensity, and the cryosurgical response of a solution of 1.5% of gelatine in water kept at a constant temperature of +30°C, and continuously stirred, are described in vitro in this study. The investigations were performed at temperatures of -40°C, -80°C, -120°C, and -180°C by means of two disc-shaped cryoprobes with diameter of 5 to 50 mm respectively, and a laparoscopic needle with a diameter of 10 mm.

Keywords

Constant Temperature Freezing Process Experimental Foundation Demarcation Line Parenchymal Organ 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 2001

Authors and Affiliations

  • Nikolai N. Korpan
  • Jaroslav V. Zharkov

There are no affiliations available

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