History of Cryosurgery

  • Nikolai N. Korpan


The use of cold temperatures as a promising technique for medical purposes has been known for a long time. It was the anesthetizing properties of cold that were first used to treat a variety of medical conditions. In comparison, the history of cryosurgery is relatively short and, in the nineteenth and twentieth centuries, closely interwoven with developments in low-temperature physics, engineering and the refinement of the necessary instruments. A review of the history of cryosurgery will show that it has progressed in leaps and that each leap has usually been triggered by technological innovations which immediately preceded it. Thus rhe possibility of creating very low temperatures of less than -100°C was immediately followed by Schroeder’s discovery in 1997 that the aplication of such low temperatures could induce cell death.


Basal Cell Carcinoma Uterine Fibroid Cold Injury Liquid Oxygen Cervical Intra Epithelial Neoplasia 
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© Springer-Verlag/Wien 2001

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  • Nikolai N. Korpan

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