The benefit of the use of cold for medical purposes has been known for a long time. The use of low temperatures, at first derived from snow and ice, was based on their anesthetizing properties and their slowing down of biological processes. Later, technical improvements made very low temperatures available which had the potential to destroy living tissue. Since then, low temperatures have found their use in virtual every specialty of medicine. But since 1968 only a few orthopedic surgeons dealing with skeletal tumors have adopted the cryosurgical technique. The clinical results and experimental data of cryosurgery with specific references to the skeletal system have been published in about 60 papers. Larger series of patients are, with only an occasional exception, not available, but are necessary for the benefits of the cryosurgery technique to be confirmed.
KeywordsProximal Tibia Giant Cell Tumor Giant Cell Tumor Eosinophilic Granuloma Tumor Cavity
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