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Challenges and Future Direction

  • Antonino F. Germanò
  • Francesco Tomasello

Abstract

Today, the role of the cerebral vasculature in the ageing brain and in the pathogenesis of chronic neurodegenerative disorders and stroke has been recognised. Strategies to circumvent vascular barriers of the CNS to deliver various recombinant proteins, enzymes, and neuropharmaceuticals to selectively target the neuronal populations in affected brain areas has become an imperative of the current neuropharmaceutical industry and an unavoidable component of the everyday lives of general practitioners and clinical neuroscientists.

Keywords

Gene Therapy Subarachnoid Haemorrhage Transient Gene Expression Cerebral Blood Vessel Herpes Simplex Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Wien 2001

Authors and Affiliations

  • Antonino F. Germanò
    • 1
  • Francesco Tomasello
    • 1
  1. 1.Department of NeurosurgeryUniversity of Messina Medical SchoolMessinaItaly

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