The central nervous system (CNS) takes its origin from the ectodermal tissue. In the blastula, those cells, which will form the CNS, invaginate to create a depression: the tips of this structure fuse in order to develop a tube. During the early stages, a single cell layer constitutes this tube. During the developmental stages, the differentiation phenomena determine the creation of flexures, folds, depressions, invaginations, and thickening of the different cerebral regions, to create the complexity of the adult CNS.


Tight Junction Ependymal Cell Brain Capillary Adult Central Nervous System Paracellular Transport 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 2001

Authors and Affiliations

  • Giuseppe Anastasi
  • Placido Bramanti

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