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Nierenzellcarcinom

  • Chapter
Urogenitale Carcinome

Part of the book series: Onkologie heute ((ONKOLOGIE))

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Zusammenfassung

Mit 85% ist das Nierenzellcarcinom (Hypernephrom, Grawitz-Tumor) der häufigste bösartige Tumor der Niere. Der überwiegende Anteil der malignen Nierentumoren sind Adenocarcinome (85%), der Rest besteht aus Nierenbeckencarcinomen (7–8%), dem Nephroblastom bzw. Wilms-Tumor (5–6%) und anderen Histologien (Tab. 1). Das mittlere Manifestationsalter der Patienten mit Nierenzellcarcinom liegt zwischen 50 und 70 Jahren. Jährlich treten in Europa sowie in den Vereinigten Staaten jeweils 30.000 Neuerkrankungen mit einer Inzidenz von 7–8/100.000 und einer zu erwartenden Todesrate von jeweils bis zu 12.000 Patienten pro Jahr auf (Landis et al. 1998, SCI AM: Fact sheet 1996). Für die Industriestaaten wird eine Zunahme der Inzidenzrate berichtet; die höchste Inzidenz besteht in Nordamerika und Skandinavien (Whitmore Jr. 1989). Männer erkranken doppelt so häufig als Frauen. Ein Drittel der Patienten weist bei Diagnosestellung bereits Metastasen auf. Die 5-Jahres-Überlebensrate der Patienten mit metastasiertem Nierenzellcarcinom beträgt < 5%; eine standardisierte Behandlung konnte bisher nicht etabliert werden (Motzer et al. 1996, Savage 1995).

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  1. Europäisches Institut für Tumor-Immunologie und Prävention (EUTIP), Gotenstraße 152, D-53175, Bonn, Deutschland

    Prof. Dr. Dr. med. Jens Atzpodien, Dipl.-Biol. Tatjana Patzelt & Dr. Martina Reitz

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  1. Prof. Dr. Dr. med. Jens Atzpodien
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  2. Dipl.-Biol. Tatjana Patzelt
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  3. Dr. Martina Reitz
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  1. Klinische Abteilung für Onkologie, Univ.-Klinik für Innere Medizin I, Allgemeines Krankenhaus, Wien, Österreich

    Christoph Zielinski

  2. Klinische Abteilung für Allgemeinchirurgie, Univ.-Klinik für Chirurgie, Allgemeines Krankenhaus, Wien, Österreich

    Raimund Jakesz

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Atzpodien, J., Patzelt, T., Reitz, M. (2001). Nierenzellcarcinom. In: Zielinski, C., Jakesz, R. (eds) Urogenitale Carcinome. Onkologie heute. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6193-7_8

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  • DOI: https://doi.org/10.1007/978-3-7091-6193-7_8

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