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Glutamate receptors as a target for Alzheimer’s disease — are clinical results supporting the hope?

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Part of the book series: Journal of Neural Transmission. Supplementa ((NEURAL SUPPL,volume 62))

Abstract

Several years after the introduction of cholinergic drugs in Alzheimer’s disease therapy, other approaches for symptomatic and also disease-modifying pharmacotherapy are progressing in their development. Among these, the NMD A antagonist memantine represents the most advanced and promising agent, gifted with many years of clinical experience in Germany. This paper provides an overview of both, the novel pharmacological background and recent clinical evidence in dementia. Memantine was recently recommended for central European approval.

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© 2002 Springer-Verlag Wien

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Winblad, B., Möbius, H.J., Stöffler, A. (2002). Glutamate receptors as a target for Alzheimer’s disease — are clinical results supporting the hope?. In: Jellinger, K.A., Schmidt, R., Windisch, M. (eds) Ageing and Dementia Current and Future Concepts. Journal of Neural Transmission. Supplementa, vol 62. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6139-5_20

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  • DOI: https://doi.org/10.1007/978-3-7091-6139-5_20

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83796-2

  • Online ISBN: 978-3-7091-6139-5

  • eBook Packages: Springer Book Archive

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