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Frequency of white matter lesions and silent lacunar infarcts

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Ageing and Dementia Current and Future Concepts

Part of the book series: Journal of Neural Transmission. Supplementa ((NEURAL SUPPL,volume 62))

Abstract

White matter lesions and silent lacunar infarcts are related to andmay result from cerebral small vessel disease. Reported frequencies of theselesions vary largely among studies. Differences in imaging techniques, ratingscales, cut-off points in lesion severity grading and study populations contribute to the variation, in addition to differences in risk factor profiles acrossstudies.

In this paper, we will firstly discuss general methodological issues that may influence reported frequencies of white matter lesions and silent lacunar infarctions, and then review published data. We will focus on the results from population-based studies and only briefly comment on patient series fo stroke and dementia.

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Authors and Affiliations

  1. Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR, Rotterdam, The Netherlands

    E. J. van Dijk, N. D. Prins, S. E. Vermeer & M. M. B. Breteler MD, PhD

  2. Department of Neurology, Rotterdam, Rotterdam, The Netherlands

    E. J. van Dijk, N. D. Prins, S. E. Vermeer & P. J. Koudstaaf

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  1. E. J. van Dijk
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  2. N. D. Prins
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  3. S. E. Vermeer
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  4. P. J. Koudstaaf
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  5. M. M. B. Breteler MD, PhD
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Editors and Affiliations

  1. Institut für Klinische Neurobiologie, Kenyongasse 18/7, A-1070, Wien, Austria

    Kurt A. Jellinger

  2. Universitätsklinik für Neurologie, Auenbruggerplatz 22, A-8036, Graz, Austria

    Reinhold Schmidt

  3. JWS Research Forschungslabor GmbH, Rankengasse 28, A-8020, Graz, Austria

    Manfred Windisch

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© 2002 Springer-Verlag Wien

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van Dijk, E.J., Prins, N.D., Vermeer, S.E., Koudstaaf, P.J., Breteler, M.M.B. (2002). Frequency of white matter lesions and silent lacunar infarcts. In: Jellinger, K.A., Schmidt, R., Windisch, M. (eds) Ageing and Dementia Current and Future Concepts. Journal of Neural Transmission. Supplementa, vol 62. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6139-5_2

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  • DOI: https://doi.org/10.1007/978-3-7091-6139-5_2

  • Publisher Name: Springer, Vienna

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