Vagus Nerve Stimulation for Epilepsy, Clinical Efficacy of Programmed and Magnet Stimulation
Rationale.Vagus nerve stimulation (VNS) by intermittent and programmed electrical stimulation of the left vagus nerve in the neck, has become widely available. It is an effective treatment for patients with refractory epilepsy. Patients can be provided with a magnet that allows to deliver additional stimulation trains. Since earlier studies have demonstrated the persistence of a stimulation effect after discontinuation of the stimulation train, we evaluated the clinical efficacy of VNS both in the programmed intermittent stimulation mode and magnet stimulation mode.
KeywordsVagus Nerve Magnet Stimulation Vagus Nerve Stimulation Seizure Frequency Refractory Epilepsy
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- 3.Woodbury DM, Woodbury JW (1990) Effects of vagal stimulation on experimentally induced seizures in rats. Epilepsia 31 [Suppl] 2: 7–19Google Scholar
- 4.Lockard JS, Congdon WC, DuCharme LL (1990) Feasibility and safety of vagal stimulation in monkey model. Epilepsia 31 [Suppl] 2: 20–26Google Scholar
- 5.Rutecki P (1990) Anatomical, pyhsiological and theoretical basis for the antiepileptic effect of vagus nerve stimulation. Epilepsia 31 [Suppl] 2: S1—S6Google Scholar
- 12.Reese T, Brent T, Zabara J (1990) An implantable neurocybernetic prosthesis system. Epilepsia 31 [Suppl] 2: S33—S37Google Scholar
- 14.Lockard JS, Congdon WC, DuCharme LL (1990) Feasability and safety of vagal stimulation: the monkey model. Epilepsia 3 [Suppl] 2: S20–26Google Scholar