Evolution of Transsphenoidal Surgery

  • P. Cappabianca
  • O. de Divitiis
  • F. Maiuri


The transsphenoidal route is the dominant approach to the pituitary and sellar area and is utilized for more than 95% of the surgical indications in this region. Pituitary adenomas represent the third most common primary intracranial tumor after gliomas and meningiomas, with a percentage of more than 15% in most series reported in the literature and are found in 20% of cases at routine autopsies for patients who do not die for pituitary disease. If we also consider the other lesions in this same area and the recently proposed extended transsphenoidal approaches [12, 24, 32, 33, 35, 36, 37, 40, 41, 43, 44, 48, 61], we should not be surprised by the figure reported by Jane Jr. et al. [30], indicating that 19% of primary brain tumors treated in academic centers in the United States are operated upon transsphenoidally.


Pituitary Adenoma Transsphenoidal Surgery Functional Endoscopic Sinus Surgery Transsphenoidal Approach Endoscopic Endonasal Surgery 
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© Springer-Verlag Wien 2003

Authors and Affiliations

  • P. Cappabianca
  • O. de Divitiis
  • F. Maiuri

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