The System of Grading of Gliomas

  • G. P. Sayre
Conference paper
Part of the Acta Neurochirurgica / Supplementum book series (NEUROCHIRURGICA, volume 10)


In this discussion of grading of tumors of the central nervous system, I would like to confine my remarks to three phases of the problem. First, the historical background of grading of tumors; second, the use of such a system as applied to gliomas in the central nervous system; and third, to discuss some of the criticisms that have arisen since the publication of the method of grading.


Mayo Clinic Intermediate Group General Pathologist Astrocytoma Grade Cerebellar Astrocytoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Broders, A. C., Sqamous Cell Epithelioma of the Lip: A Study of Five Hundred and thirty-seven Cases. J. A. M. A. 74 (1920), 656–664.CrossRefGoogle Scholar
  2. 2.
    Broders, A.C., The Grading of Carcinoma. Minnesota Med. 8 (1925), 76–730.Google Scholar
  3. 3.
    Bailey, P., and H. Gushing, A Classification of the Tumors of the Glioma Group on a Histogenetic Basis with a Correlated Study of Prognosis. Philadelphia; The J. B. Lippincott Company. 1926.Google Scholar
  4. 4.
    Kernohan, J. W., R. F. Mabon, H. J. Svien, and A. W. Adson, A Simplified Classification of Gliomas. Proc. Staff Meet. Mayo Clin. 24 (1949), 71–75.PubMedGoogle Scholar
  5. 5.
    Kernohan, J. W., and G.P. Sayre, Tumors of the Central Nervous System. Atlas of Tumors Pathology Section X, Fascicles 35 and 37. Washington, D. C., Armed Forces Institute of Pathology. 1952.Google Scholar
  6. 6.
    Kerno-han, J. W., and G. P. Sayre, In: Cancer, Raven, R. W., Editor, pp. 525–551. London, Butterworth & Co. 1958.Google Scholar
  7. 7.
    Cohnheim, J., Lectures on General Pathology: A Handbook for Practitioners and Students. (Translated from the Second German Edition by A. B. McKee.) London: The New Sydenham Society. 2 (1889), 746–821.Google Scholar
  8. 8.
    Ribbert, H., Quoted by Scherer.Google Scholar
  9. 9.
    Kennaway, E. L., Experiments on Cancer Producing Substances. Brit. Med. J. 2 (1925), 1–4.PubMedCrossRefGoogle Scholar
  10. 10.
    Roussy, G., and C. Oberling, Les Tumeurs des Centres Nerveux et des Nerfs Peripheriques Paris: Atlas du Cancer, Fascicles 9 et 10. Alcon. 1931.Google Scholar
  11. 11.
    Cox, L. B., Observations Upon the Nature of Rate of Growth and Operability of the Intracranial Tumors Derived from 135 Patients. Med. J. Australia 1 (1934), 182–196.Google Scholar
  12. 12.
    Bailey, P., Histologic Diagnosis of Tumors of the Brain. Arch. Neurol. Psychiatr., London, 27 (1932), 1290–1297.Google Scholar
  13. 13.
    Cushing, H., Intracranial Tumors. Springfield and Baltimore: C. C. Thomas & Co. 1932.Google Scholar
  14. 14.
    Penfield, W., The Classification of Gliomas. Arch. Neurol. Psychiatr., London, 26 (1931), 745–753.Google Scholar
  15. 15.
    Globus, J.H., and I. Strauss, Spongioblastoma Multiforme. Arch. Neurol. Psychiatr. 14 (1925), 139–191.Google Scholar
  16. 16.
    Globus, J. H., and R. M. Cares, Neuroepithelioma. Its Place in Histogenetic Classification of Primary Neuroectodermal Brain Tumors. J. Neuropath., Baltimore, 12 (1953), 311–348.Google Scholar
  17. 17.
    Scherer, H. J., Critical Review of Pathology of Cerebral Gliomas. J. Neurol., London, 3 (1940), 147–177.Google Scholar
  18. 18.
    Calvo, W., Tumores Encefalomedu-lares. V Supplement, Archivo espan. morf. 1954.Google Scholar
  19. 19.
    Ringertz, N., “Grading” of Gliomas. Acta path, microbiol., Scand. 27 (1950), 51–64.CrossRefGoogle Scholar
  20. 20.
    Zülch, K.J., The Present State of the Classification of Intracranial Tumour and Its Value for the Neurosurgeon. Rev. brasil. cir. 40 (1960), 247–264. In: Fields and Sharkey and coll., The Biology and Treatment of Intracranial Tumors. Chapter VII, p. 157–177. Ch. C.Thomas Publ., Springfield, Ill., 1962.Google Scholar
  21. 21.
    Dukes, C.E, The Classification of Cancer of the Rectum. J. Path. Bact. 3 (1932), 323–332.CrossRefGoogle Scholar
  22. 22.
    Dochat, G. R., A Prognostic Comparison of Serosal and Nodal Spread in Carcinoma of the Stomach with Classification into Duke’s Types. Thesis Univ. of Minn. 1941.Google Scholar

Copyright information

© Springer-Verlag/Wien 1964

Authors and Affiliations

  • G. P. Sayre

There are no affiliations available

Personalised recommendations