Summary
In this preliminary study, children with chronic HBV hepatitis, as was also previously shown for adults, respond to interferon therapy in an HLA class I antigen dependent manner. If this can be confirmed on a large scale, HLA typing may serve as a useful indication of interferon-therapy responders.
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References
Forzani B, Actis GC, Verme G (1984) HLA-DR antigens in HBsAg positive chronic active liver disease with and without associated delta infection. Hepatology 4:1107–1110
Hillis WD, Hillis A, Bias WB, WGB (1977) Association of hepatitis B surface antigenemia with HLA locus B Walker specificities. N Engl J Med 296: 1310–1314
van Hattum J, Schreuder GMT, Schalm SW (1987) HLA antigens in patients with various courses after hepatitis B virus infection. Hepatology 7: 11–14
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© 1992 Springer-Verlag
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Giacchino, R. et al. (1992). Association between HLA class I antigens and response to interferon therapy in children with chronic HBV hepatitis. In: De Bac, C., Taliani, G., Gerlich, W.H. (eds) Chronically Evolving Viral Hepatitis. Archives of Virology, vol 4. Springer, Vienna. https://doi.org/10.1007/978-3-7091-5633-9_63
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DOI: https://doi.org/10.1007/978-3-7091-5633-9_63
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82350-7
Online ISBN: 978-3-7091-5633-9
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