Hepatitis in pre-school children: prevalent role of cytomegalovirus
Virological and serological investigations were performed on 8 children with clinical and/or laboratory signs of hepatitis. Cytomegalovirus (CMV) appeared as the most frequently involved etiologic agent, since it was associated with 5 severe or chronically-evolving cases. Out of the other 3 patients with non-CMV associated hepatitis, all completely recovering, two had clinically typical Epstein-Barr virus infections, while the remaining patient had an asymptomatic HBV infection.
KeywordsSerological Investigation Neonatal Hepatitis Congenital Cytomegalovirus Infection Liver Histological Examination Virus Infectious Mononucleosis
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- 2.Chang M-H, Hsu H-C, Lee C-Y, Wang T-R, Kao C-L (19,87) Neonatal hepatitis: a follow-up study. J Pediatr Gastroenterol Nutr 6: 203–207Google Scholar
- 5.Ho M (1990) Cytomegalovirus. In: Mandell GL, Douglas RG Jr, Bennett JE (eds) Principles and practice of infectious diseases, 3rd edn. Churchill Livingstone, New York Edinburgh London MelbourneGoogle Scholar
- 12.Sumaya CV, Ench Y (1985) Epstein-Barr virus infectious mononucleosis in children. I. Clinical and general laboratory findings. Pediatrics 75: 1003–1010Google Scholar
- 14.Toghill PJ, Williams R, Stern H (1969) Cytomegalovirus infection and chronic liver disease. Gastroenterology 56: 635–637Google Scholar
- 15.Tucciarone L, Felici W, Nigro G, Mechelli A, Castelvetere M, Olivo G (1989) Un caso di malattia citomegalica acquisita a decorso fatale. Riv Ital Pediatr 15: 643–646Google Scholar