Hepatitis in pre-school children: prevalent role of cytomegalovirus

  • G. Nigro
  • S. Mattia
  • R. Vitolo
  • U. Bartmann
  • M. Midulla
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)


Virological and serological investigations were performed on 8 children with clinical and/or laboratory signs of hepatitis. Cytomegalovirus (CMV) appeared as the most frequently involved etiologic agent, since it was associated with 5 severe or chronically-evolving cases. Out of the other 3 patients with non-CMV associated hepatitis, all completely recovering, two had clinically typical Epstein-Barr virus infections, while the remaining patient had an asymptomatic HBV infection.


Serological Investigation Neonatal Hepatitis Congenital Cytomegalovirus Infection Liver Histological Examination Virus Infectious Mononucleosis 


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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • G. Nigro
    • 2
  • S. Mattia
    • 1
  • R. Vitolo
    • 2
  • U. Bartmann
    • 2
  • M. Midulla
    • 1
  1. 1.Pediatric Institute of “La Sapienza” UniversityRomeItaly
  2. 2.Pediatric Institute of Experimental Medicine of the National Council of ResearchRomeItaly

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