Summary
The prevalence of anti-C100-3 increases with age from 0.41% to 1.26%. It is more frequent in donors with elevated ALT (4.5%). Most ALT elevations, however, are not related to anti-C100-3. Low EIA signals (<3 x cutoff) are often non-specific. The cutofï value should be 2.5 times higher. High EIA signals correlate with ALT elevations.
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References
Weiner AJ, Truett MA, Rosenblatt J, Han J, Quan S, Polito AJ, Kuo G, Choo Q-L, Houghton M, Agius C, Page E, Nelles MJ (1990) HCV testing in low-risk population. Lancet 336: 695
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© 1992 Springer-Verlag
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Caspari, G., Beyer, HJ., Gerlich, W.H., Schmitt, H. (1992). Assay of antibodies to hepatitis C virus protein C100-3 in blood donors from Northern Germany. In: De Bac, C., Taliani, G., Gerlich, W.H. (eds) Chronically Evolving Viral Hepatitis. Archives of Virology, vol 4. Springer, Vienna. https://doi.org/10.1007/978-3-7091-5633-9_56
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DOI: https://doi.org/10.1007/978-3-7091-5633-9_56
Publisher Name: Springer, Vienna
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