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HCV and blood transfusion

  • H. W. Reesink
  • C. L. van der Poel
  • H. T. M. Cuypers
  • P. N. Lelie
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)

Summary

Posttransfusion hepatitis remains a threat to transfusion therapy. Testing for increased ALT levels has been used in an attempt to reduce this risk. Presence of the infectious agent, hepatitis C virus (HCV), appears to be a much more sensitive criterion. Stored serum samples from transfusion blood as well as recipients of transfusion were tested by ELISA, RIB A and PCR for the presence of HCV. The results show that RIBA and PCR are about equally sensitive and are able to detect HCV positivity in many sera that might have been otherwise transfused. Routine screening for the presence of virus will dramatically reduce the danger of hepatitis infection to transfusion patients.

Keywords

Transfusion Therapy Posttransfusion Hepatitis Store Serum Sample Blood Donor Screening Recombinant Immunoblot Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • H. W. Reesink
    • 1
  • C. L. van der Poel
    • 1
  • H. T. M. Cuypers
    • 2
  • P. N. Lelie
    • 2
  1. 1.Red Cross Blood Bank AmsterdamAmsterdamThe Netherlands
  2. 2.Central Laboratory of the NetherlandsAmsterdamThe Netherlands

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