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Antibodies to hepatitis C virus in primary biliary cirrhosis

  • E. Bertolini
  • F. Marelli
  • P. Zermiani
  • P. M. Battezzati
  • M. Zuin
  • G. A. Moroni
  • M. Podda
Conference paper
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)

Summary

We investigated the prevalence of anti-HCV in 160 consecutive patients with primary biliary cirrhosis. By ELISA, 19 (12%) were positive, as compared to a 68% prevalence in 135 patients with chronic non-A, non-B hepatitis. Serum IgG levels were significantly higher in the anti-HCV positive group. By RIBA, seropositivity was confirmed for 4 patients, whereas 7 were indeterminate. A slight, non-significant reduction of life expectancy was found in anti-HCV positive patients. Until reliable and independent confirmatory tests become available, definitive conclusions on the importance of anti-HCV positivity in primary biliary cirrhosis are improper.

Keywords

Primary Biliary Cirrhosis Autoimmune Hepatitis Primary Biliary Cirrhosis Patient Autoimmune Liver Disease Conventional ELISA 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • E. Bertolini
    • 2
  • F. Marelli
    • 1
  • P. Zermiani
    • 1
  • P. M. Battezzati
    • 1
  • M. Zuin
    • 2
  • G. A. Moroni
    • 1
  • M. Podda
    • 1
  1. 1.Department of Internal Medicine, Istituto di Scienze Biomediche Ospedale S. PaoloUniversity of MilanMilanoItaly
  2. 2.Blood Transfusion Center, Ospedale S. PaoloMilanoItaly

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