Identification of HCV-associated antigen(s) in hepatocytes
HCV-associated antigens (HCAg) were localized morphologically using immunofluorescence methods. Fluorescence was found in the cytoplasm of individual liver cells or in groups of cells. Nuclear fluorescence was not observed. Blocking and absorption studies suggest that HCAg is related to nucleocapsid or envelope proteins.
KeywordsLiver Biopsy Specimen Chronic Persistent Hepatitis Posttransfusion Hepatitis Nuclear Fluorescence Liver Cell Nucleus
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- 2.Kuo G, Choo Q-L, Alter H, Gitnick GL, Redeker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE, Tegtmeier GE, Bonino M, Colombo M, Lee WS, Berger K, Shuster JR, Överby LR, Bradley DW, Houghton M (1989) An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244: 362–364PubMedCrossRefGoogle Scholar