Summary
We have studied the T-cell processing pathways of Hepatitis B antigens and the role of specific B lymphocytes. It could be shown that some form of processing by specific B cells is required for class I CTLs. This mechanism differs from class II endosomal processing. In addition, it could be shown that lysis of HBsAg-specific B cells may be partly responsible for chronic HBV carrier states.
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© 1992 Springer-Verlag
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Barnaba, V., Franco, A., Paroli, M., Benvenuto, R., Santilio, I., Balsano, F. (1992). T cell recognition of hepatitis B envelope proteins. In: De Bac, C., Taliani, G., Gerlich, W.H. (eds) Chronically Evolving Viral Hepatitis. Archives of Virology, vol 4. Springer, Vienna. https://doi.org/10.1007/978-3-7091-5633-9_4
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DOI: https://doi.org/10.1007/978-3-7091-5633-9_4
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82350-7
Online ISBN: 978-3-7091-5633-9
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