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Enhanced luminescent assays for hepatitis markers: Assessment of post vaccine responses

  • Elizabeth H. Boxall
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)

Summary

A range of solid phase immunoassays have been developed using enhanced chemiluminescence to provide a signal which can be measured in a qualitative or quantitative manner. The “Amerlite” anti-HBs assay has been used routinely to test more than 3000 post-vaccine anti-HBs levels. The results show that 5% of vaccinees are non-responders, but that more than 30% produce antibody levels greater than 1000 mIU/ml.

Keywords

Wide Dynamic Range Health Care Staff Luminescent Assay Advise Health Care Radio Immunoassay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Atherton CJ, Boxall EH (1986) A sensitive screening test of the simultaneous detection of hepatitis B surface antigen and antibody. J Virol Met 13: 245–253CrossRefGoogle Scholar
  2. 2.
    Lane RS (1981) Hepatitis B surface antigen testing: The blood products laboratory radio immunoassay (BPL/RIA) system. Med Lab Sci 38: 323–329PubMedGoogle Scholar
  3. 3.
    Wheeley SM, Boxall EH, Tarlow MJ, Gatrad AR, Anderson J, Bissenden J, Chin KC, Mayne A (1990) Hepatitis B Vaccine in the prevention of perinatally transmitted hepatitis B virus infection: J Med Virol 30: 113–116PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Elizabeth H. Boxall
    • 1
  1. 1.Regional Virus LaboratoryBirmingham, West MidlandsEngland, UK

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