Functions of hepatitis B surface proteins
HBV surface proteins play a number of functional roles in cellular infection, viral synthesis and in immune responses of the host. Three coterminal proteins of differing sizes and three subdomains of the individual molecules can be recognized. In this brief review, functions of the various proteins and domains are described and their significance as potential immunogens is discussed. Although it is apparent that the surface proteins are involved in the development of persistent HBV infections, the underlying mechanisms of their involvement remain unknown.
KeywordsHuman Serum Albumin Human Serum Albumin Binding Free Human Serum Albumin Native Human Serum Albumin Asymptomatic HBsAg Carrier
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