HBc and HBe specificity of monoclonal antibodies against complete and truncated HBc proteins from E. coli

  • E. Korec
  • W. H. Gerlich
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)


We have prepared and used monoclonal antibodies against various populations of full-length and truncated hepatitis B core proteins in order to distinguish between epitopes of HBcAg and HBeAg. Our results show that various epitopes are specific for the different proteins. Certain epitopes, however, are ubiquitous to HBc/e proteins and these are probably exposed on the surface of HBc particles.


Core Antigen Associate Protein Kinase Virus Associate Protein Carboxy Terminal Domain 41F4 IgG2A 
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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • E. Korec
    • 1
  • W. H. Gerlich
    • 2
  1. 1.Institute of Molecular GeneticsPragueCSFR
  2. 2.Department of Medical MicrobiologyUniversity of GöttingenFederal Republic of Germany

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