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Lack of pre-C region mutation in woodchuck hepatitis virus from seroconverted woodchucks

  • S. P. Tong
  • L. Vitvitski
  • J. S. Li
  • C. Pichoud
  • C. Trépo
Conference paper
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)

Summary

Woodchuck hepatitis virus, which shares a large degree of homology with human HBV, was examined for indications of mutational variants. No alteration in the pre-C region was found, but as in HBV, viral DNA could still be detected by PCR after seroconversion to anti-WHe.

Keywords

Chronic Hepatitis Nonsense Mutation Nucleotide Difference Mutational Variant Positive Serum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Galibert F, Chen TN, Mandart E (1982) J Virol 41: 51–65PubMedGoogle Scholar
  2. 2.
    Kaneko S, Miller RH, Feinstone SM, Unoura M, Kobayashi K, Hattori N, Purcell RH (1989) Proc Natl Acad Sci USA 86: 312–316PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • S. P. Tong
    • 1
  • L. Vitvitski
    • 1
  • J. S. Li
    • 1
  • C. Pichoud
    • 1
  • C. Trépo
    • 1
  1. 1.INSERM U.271LyonFrance

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