Prevalence of antibodies to hepatitis C virus in patients with hepatocellular carcinoma in Austria

  • Martina Baur
  • U. Hay
  • G. Novacek
  • C. Dittrich
  • P. Ferenci
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)


In 12 of 54 (22%) patients with histologically verified hepatocellular carcinoma, antibodies to hepatitis C virus were found. In patients with hepatocellular carcinoma the frequency of anti-hepatitis C virus positivity was similar whether cirrhosis (6 of 22 patients (27%)) was present or not (2 of 15 (13%)). Out of 54, 23 patients (43%) were negative both for hepatitis B or C markers. Out of 53,22 (42%) had positive hepatitis B markers, 8 of 22 were HBsAg positive. Patients with hepatocellular carcinoma and cirrhosis had a higher percentage of hepatitis B virus markers than patients with cirrhosis without hepatocellular carcinoma. Out of 70 patients with cirrhosis but without hepatocellular carcinoma, 24 (34%) had antibodies to hepatitis C virus. Our data of similar frequencies of antibodies to hepatitis C virus in patients with hepatocellular carcinoma or with liver cirrhosis but without hepatocellular carcinoma indicate that at least in Austrian patients, hepatitis C virus infections are not an important factor for development of hepatocellular carcinoma.


Hepatocellular Carcinoma Liver Cirrhosis Austrian Patient nonB Hepatitis Serum Globulin Concentration 
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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Martina Baur
    • 1
  • U. Hay
    • 2
  • G. Novacek
    • 1
  • C. Dittrich
    • 3
  • P. Ferenci
    • 1
  1. 1.I. Department of Gastroenterology and HepatologyUniversity of ViennaWienAustria
  2. 2.II. Department of Gastroenterology and HepatologyUniversity of ViennaAustria
  3. 3.Department of ChemotherapyUniversity of ViennaWienAustria

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