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Immune pathogenesis of hepatitis A

  • A. Vallbracht
  • B. Fleischer
Part of the Archives of Virology book series (ARCHIVES SUPPL, volume 4)

Summary

In an effort to elucidate the mechanism of liver damage resulting from Hepatitis A virus (HAV) infection, we have studied infected skin fibroblasts and autologous lymphocytes from HAV patients. We report here that HLA-restricted virus-specific T cells play an essential role in HAV-related hepatocellular injury.

Keywords

Cytolytic Activity Hepatocellular Injury Versus Patient Autologous Lymphocyte Normal Human Hepatocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • A. Vallbracht
    • 1
  • B. Fleischer
    • 2
  1. 1.Abteilung Medizinische VirologieUniversität TübingenTübingenFederal Republic of Germany
  2. 2.I Medizinische KlinikUniversität MainzFederal Republic of Germany

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