Chemical Control of Excitable Membranes during Electrical Activity
Excitable membranes are endowed with the «special ability to change rapidly permeability to ions. The ion movements thereby effected are the carriers of electric currents which propagate nerve impulses along nerve and muscle fibers. There is no alternative to the assumption that these extremely precise, specific, rapid and reversible changes of the membrane permeability are controlled by chemical reactions. The small initial heat during the activity of nerve fibers, measured some 40 years ago by A. V. Hill and his associates, was attributed by H o d g ki n , in 1951, to ion mixing, thereby excluding chemical processes. The recent heat production measurements of A. V. Hill and his associates  have virtually eliminated this interpretation.
KeywordsGiant aXons Mount Sinai Hospital Excitable Membrane Ranvier Node Cement Reaction
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