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The Effect of Prostaglandin E1 on Free Fatty Acid Mobilization and Transport

  • F. Berti
  • R. Lentati
  • M. M. Usardi
  • R. Paoletti
Conference paper

Abstract

Prostaglandin E1 (PGE1: 11 alpha, 15 dihydroxy-9-keto-prost-13 enoic acid) is the best known of a series of lipid soluble acidic compounds (prostaglandins) present in mammalian tissues and biological fluids [1, 2]. The prostaglandins include several closely related components isolated and elucidated from the point of View of their chemical structure by Bergström et al. [3, 4]. They are hiosynthesized in mammalian organisms from the corresponding polyunsaturated fatty acids (arachidonic, homo-gamma-linolinic acid [5] and exhibit biological activity in vitro and in vivo at extremely low concentrations: vasodepression [6], smooth (muscle contraction [7, 8] and inhibition of free fatty acid release from adipose tissue [9, 10, 11].

Keywords

Free Fatty Acid Muscular Dystrophy Plasma Free Fatty Acid Glycerol Release Enoic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1967

Authors and Affiliations

  • F. Berti
    • 1
  • R. Lentati
    • 1
  • M. M. Usardi
    • 1
  • R. Paoletti
    • 1
  1. 1.Institute of PharmacologyUniversity of MilanMilanItaly

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