Energy Metabolism and Ion Transport Studied in Single Neurons

  • Ezio Giacobini
Conference paper


The stretch receptor organ of crustaceans allows us to work with, a whole, intact and isolated neuron which can be kept in apparently normal functional condition for several hours and in which impulse activity as well as oxygen uptake (Giacobini 1963 and 1965 a), enzymatic activity, substrates and ion concentrations (Giacobini 1965 a, Giacobini and Grasso 1966, Giacobini and Marchisio 1966 a, Giacobini and Karlsson 1965, Giacobini 1965 b) can be studied1. The increase in oxygen uptake which follows impulse activity is a function of the impulse frequency and is not dependent on the external K+ and Ca++ concentrations (Giacobini 1965 a, Giacobini et al. 1965).


Oxygen Uptake Impulse Activity Electric Organ Pyridine Nucleotide Impulse Frequency 
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Copyright information

© Springer-Verlag/Wien 1967

Authors and Affiliations

  • Ezio Giacobini
    • 1
  1. 1.Department of PharmacologyKarolinska InstitutetStockholmSweden

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