Energy Metabolism and Ion Transport Studied in Single Neurons
The stretch receptor organ of crustaceans allows us to work with, a whole, intact and isolated neuron which can be kept in apparently normal functional condition for several hours and in which impulse activity as well as oxygen uptake (Giacobini 1963 and 1965 a), enzymatic activity, substrates and ion concentrations (Giacobini 1965 a, Giacobini and Grasso 1966, Giacobini and Marchisio 1966 a, Giacobini and Karlsson 1965, Giacobini 1965 b) can be studied1. The increase in oxygen uptake which follows impulse activity is a function of the impulse frequency and is not dependent on the external K+ and Ca++ concentrations (Giacobini 1965 a, Giacobini et al. 1965).
KeywordsOxygen Uptake Impulse Activity Electric Organ Pyridine Nucleotide Impulse Frequency
Unable to display preview. Download preview PDF.
- Giacobini, E., 1963 b: Abstr. IX Physiol. Congr. Copenhagen, 59. Acta Physiol. Scand., Suppl. 213.Google Scholar
- Giacobini, E., 1965 a: In: Drugs and Enzymes, Vol. IV (B. Brodie ed.), Pergarnon Press, pp. 55–63.Google Scholar
- Giacobini, E., 1965 b: (In press.)Google Scholar
- Giacobini, E., 1965 c: Annali Istit. Super. Sanità 1, 500–520.Google Scholar
- Giacobini, E., and P. C. Marchisi o, 1965: Acta Physiol. Scand. (In press.)Google Scholar
- Giacobini, E., and B. Karls so n, 1965: (In press.)Google Scholar
- Giacobini, E., E. Handelmann, and P. C. Terzuolo, 1965: (In press.)Google Scholar
- Lowry, O. H., and J. V. Passonnean, Personal communication.Google Scholar
- Whittam, R., 1964: Transport and Diffusion in red blood cells. E. Arnold Ltd. (London), pp. 141–142.Google Scholar