Profound Hypothermia and Total Circulatory Arrest in Neurosurgery: Methods, Results, and Physiologic Effects
Until recently hypothermia in neurosurgery had been limited to surface technics and temperatures of about 28° C; the potential hazard of ventricular fibrillation precluded further cooling. The development of extracorporeal perfusion technics has effectively circumvented this limiting factor, permitting temperatures to be lowered to 15° C and below with little additional hazard to the patient. At these temperatures the oxygen requirements are such that the brain and other vital organs can withstand total circulatory arrest for periods of 30 to 40 minutes without apparent damage.
KeywordsIntracranial Aneurysm Circulatory Arrest Stroke Index Cent Carbon Dioxide Profound Hypothermia
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