The Enzymology of the Cell Surface

  • Aser Rothstein
Part of the Protoplasmatologia book series (PROTOPLASMATOL., volume 2 / E / 4,5)


In recent years there has been a convergence of interest on the part of the biochemists on one hand and the biologists and cytologists on the other. The biochemist has become increasingly aware that biochemical activities of the cell are intimately related to the structure of the cell. The biologist has become increasingly aware that the morphological elements of the cell possess important metabolic functions. The common interest of the biochemist and the biologist has resulted in the present popularity of research concerned with the localization of enzyme systems within the cell. Considerable impetus has also been given to such studies by the development of techniques which allow the isolation of cellular elements such as the mitochondria, microsomes, chloroplasts and nuclei. In addition new cytological techniques such as electron microscopy, autoradiography, and ultraviolet microscopy, as well as the more recent modifications of staining procedures, have increased our knowledge of the metabolic geography of the cell. Not only has it become apparent that specific enzymes are intimately associated with certain structural elements of the cell, but it is evident that the architecture of the cell plays an important role in the regulation of metabolic activities.


Yeast Cell Phosphate Uptake Sugar Uptake Sugar Phosphate Bivalent Cation 
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© Springer Verlag 1954

Authors and Affiliations

  • Aser Rothstein
    • 1
  1. 1.Division of Pharmacology, Department of Radiation BiologyUniversity of Rochester School of Medicine and DentistryRochesterUSA

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