Reproductive Issues in Multiple Sclerosis: Parental MS and Child Outcomes (The Research Perspective)

  • Neda Razaz
  • K. S. Joseph
  • Ruth Ann Marrie
  • Helen Tremlett


Approximately 10% of children live in households where a parent has a chronic illness and many children are exposed to a parent coping with a potentially disabling chronic condition, such as multiple sclerosis (MS). The disease course of MS is largely unpredictable. The uncertainty over future disability constitutes a potential threat to a patient’s mental health and makes MS a particularly challenging illness. Furthermore, due to an array of potential health effects, including physical and cognitive disability, and the caregiving tasks MS imposes on the family members, the disease may compromise parenting and cause considerable stress and anxiety on patients and their families. Indeed, childhood anxiety is a common factor identified in the sparse literature examining children of parents with MS. Few studies have shown that children with an MS parent are at risk for adjustment disorders, particularly internalizing difficulties, which could cause depressive disorders later in life. Nevertheless, not all such experiences result in negative impacts: studies have associated parental chronic illness, such as MS, with positive outcomes such as pro-social behavior and higher personal competence.


Multiple Sclerosis Anxiety Disorder Early Development Instrument Mental Health Comorbidity Developmental Health 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 2017

Authors and Affiliations

  • Neda Razaz
    • 1
    • 2
  • K. S. Joseph
    • 1
    • 2
  • Ruth Ann Marrie
    • 3
  • Helen Tremlett
    • 4
    • 5
  1. 1.School of Population and Public HealthFaculty of Medicine, University of British ColumbiaVancouverCanada
  2. 2.Department of Obstetrics and GynaecologyFaculty of Medicine, University of British ColumbiaVancouverCanada
  3. 3.Departments of Internal Medicine and Community Health SciencesUniversity of ManitobaWinnipegCanada
  4. 4.Division of Neurology, Centre for Brain Health and Department of MedicineFaculty of Medicine, University of British ColumbiaVancouverCanada
  5. 5.Vancouver Coastal Health Research InstituteVancouverCanada

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