Summary
All of the principal types of brain damage that occur in man as a result of a non-missile head injury, viz. cerebral contusions, intracranial haematoma, raised intracranial pressure, diffuse axonal injury, diffuse hypoxic damage, and diffuse swelling have been produced in subhuman primates subjected to inertial, i.e. non-impact, controlled angular acceleration of the head through 60° in the sagittal, oblique and lateral planes.
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References
Adams, J. H., Graham, D. l., The relationship between ventricular fluid pressure and the neuropathology of raised intracranial pressure. Neuropathol. Appl. Neurobiol. 2 (1976), 323–332.
Adams, J. H., Gennarelli, T. A., Graham, D. I., Brain damage in non-missile head injury. In: Recent advances in neuropathology, Vol. 2 (Smith, W. T., Cavanagh, J. B., eds.), pp. 165–190. Edinburgh-London-Melbourne-New York: Churchill Livingstone. 1983.
Adams, J. H., Graham, D. I., Diffuse brain damage in non-missile head injury. In: Recent advances in histopathology, Vol. 12 (Anthony, P. P., MacSwecn, R. N. M., eds.). Edinburgh-London-Melbourne-New York: Churchill Livingstone. In press.
Adams, J. H., Graham, D. I., Gennarelli, T. A., Acceleration induced head injury in the monkey. II. Neuropathology. Acta Neuropathol. ( Berl. ), Suppl. VII (1981), 26–28.
Adams, J. H., Graham, D. I., Gennarelli, T. A., Neuropathology of acceleration-induced head injury in the subhuman primate. In: Head injury: Basic and clinical aspects (Grossman, R. G., Gildenberg, P. L., eds.), pp. 141–150. New York: Raven Press. 1982.
Adams, J. H., Graham, D. T., Murray, L. S., Scott, G., Diffuse axonal injury due to non-missile head injury in humans: an analysis of 45 cases. Ann. Neurol. 12 (1982), 557–563.
Adams, J. H., Graham, D. I., Scott, G., Parker, L. S., Doyle, D., Brain damage in fatal non-missile head injury. J. Clin. Pathol. 33 (1980), 1132–1145.
Adams, J. H., Mitchell, D. E., Graham, D. I., Doyle, D., Diffuse brain damage of immediate impact type. Its relationship to “primary brain stem damage” in head injury. Brain 100 (1977), 489–502.
Adams, J. H., Scott, G., Parker, L. S., Graham, D. I., Doyle, D., The contusion index: a quantitative approach to cerebral contusions in head injury. Neuropathol. Appt. Neurobiol. 6 (1980), 319–324.
Gennarelli, T. A., Head injury in man and experimental animals: clinical aspects. Acta Neurochir. (Wien), 32 (1983), 1–13.
Gennarelli, T. A., Spielman, G. M., Langfitt, T. W., et al., Influence of the type of intracranial lesion on outcome from severe head injury: a multicenter study using a new classification system. J. Neurosurg. 56 (1982), 26–32.
Gennarelli, T. A., Thibault, L. E., Adams, J. H., Graham, D. I., Thompson, C. J., Marcincin, R. P., Diffuse axonal injury and traumatic coma in the primate. Ann. Neurol. 12 (1982), 564–574.
Graham, D. I., Adams, J. H., Doyle, D., Ischaemic brain damage in fatal non-missile head injuries. J. Neurol. Sci. 39 (1978), 213 234.
Graham, D. I., McLellan, D., Adams, J. H., Doyle, D., Kerr, A., Murray, L. S., The neuropathology of the vegetative state and severe disability after non-missile head injury. Acta Neurochir. (Wien), Suppl. 32 (1983), 65–67.
Peerless, S. J., Rewcastle, N. B., Shear injuries of the brain. Can. Med. Assoc. J. 96 (1967), 577–582.
Scott, G., Kerr, A., Murray, L. S., A computerized data retrieval system for brain damage in fatal non-missile head injury. Acta Neurochir. (Wien),. 32 (1983), 95–97.
Strich, S. J., Diffuse degeneration of the cerebral white matter in severe dementia following head injury. J. Neurol. Neurosurg. Psychiat. 19 (1956), 163–185.
Strich, S. J., Shearing of nerve fibres as a cause of brain damage due to head injury. Lancet 2 (1961), 443–448.
Zimmerman, R. A., Bilaniuk, L. T., Gcnarelli, T. A., Computerised tomography of shearing injuries of the cerebral white matter. Radiology 127 (1978), 393–396.
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© 1983 Springer-Verlag Wien
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Adams, J.H., Graham, D.I., Gennarelli, T.A. (1983). Head Injury in Man and Experimental Animals: Neuropathology. In: Adams, J.H. (eds) Trauma and Regeneration. Acta Neurochirurgica Supplementum, vol 32. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4147-2_2
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DOI: https://doi.org/10.1007/978-3-7091-4147-2_2
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-81775-9
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