Drug Protection for Head Injuries

  • F. Murillo
  • M. A. Muñoz
  • P. Albert
Part of the Advances in Neurotraumatology book series (NEUROTRAUMATOL., volume 2)


High dosage barbiturates to reduce intracranial pressure which is resistant to osmotic agents were first successfully employed by Ishii1. Since that time, interest in this new method has increased. Its clinical use has expanded in recent years and there have been many important papers written not only about the effectiveness of barbiturates in lowering intracranial pressure 2–5 but of their value in improving the outcome of patients suffering from head injuriesbs6–8. As the use of this therapeutic method has spread, so has the controversy as to its ability to reduce mortality and morbidity.


Head Injury Intracranial Pressure Intracranial Hypertension Cerebral Perfusion Pressure Severe Head Injury 
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Copyright information

© Springer-Verlag Wien 1987

Authors and Affiliations

  • F. Murillo
    • 1
  • M. A. Muñoz
    • 1
  • P. Albert
    • 1
  1. 1.SevilleSpain

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