Preliminary Studies of the Membrane-Associated Portion of the Hemagglutinin
Like other ‘intrinsic’ membrane proteins the hemagglutinin is amphipathic. The results of comparative analyses of intact hemagglutinin molecules and preparations which lack the membrane associated hydrophobic region indicate that the portion of the molecule associated with the lipid bilayer is near the COOHterminus of the smaller polypeptide component, HA2 (Skehel and Waterfield, 1975).
KeywordsInfluenza Virus Sucrose Density Gradient Centrifugation Detergent Micelle Chick Embryo Fibroblast Influenza Virus Hemagglutinin
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