Antigenic Determinants on the Hemagglutinin Subunits of Influenza a Viruses and Their Role in Immunity
The hemagglutinin (HA) molecule of influenza virus is a glycoprotein of mol. wt. 210,000 and is composed of 3 subunits. The polypeptide chains making up each subunit may be cleaved or uncleaved depending on the host cell in which it was grown, in the cleaved state there are two glycopolypeptide chains HA1 and HA2 of mol. wt. 47,000 and 23,000, respectively (Schulze, 1975).
KeywordsInfluenza Virus Antibody Response Cross Reaction Antigenic Determinant Specific Determinant
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